RESEARCH NODE 3: Antimicrobial Resistance (AMR) - LED BY (Spoke): UNICT

Research node 3 is organized into five interconnected WPs to address major questions on the acquisition, expression, diffusion, diagnosis and treatments of MDR microorganisms. Activities range from basic "omic" approaches to preclinical translational models, development of new diagnostics, and innovative systems to treat MDR infections and implementation of novel mathematical models to apply to the precision medicine.

Institutions involved: UNIBO - UNIPV - CNR - UNISI - UNICA - UNIPD - UNISAP - UNIMI - UNINA - UNIBA - UNITO - ISS - AIZS - HUNIMED - IRFMN - OPBG - UCSC - ISMETT - FPCBM

RESEARCH NODE 3 WORK-PACKAGE STRUCTURE:

• WP3.1 - Genomics, transcriptomics, mobilomics in MDR bacteria - One Health perspective
• WP3.2 - Preclinical translational models and studies of microorganism, human and environment correlation (Infectome)
• WP3.3 - Molecular monitoring of resistance genes and commonly associated bacterial species; preparation of microorganism-specific multigene panels for clinical, animal, and environmental matrices
• WP3.4 - Non-conventional and alternative approaches to find new anti MDRO strategies and/or as adjuvant of already existing antibiotics
• WP3.5 - Clinical relevance of "Target and Tailored" therapies

RESEARCH NODE 3 ADDITIONAL PROJECTS:

• Cascade Open Call 2023 Spoke 3 Winner :
  Rapid prediction and diagnosis of SEPsis in Solid Organ Transplant: The Italian national initiative for an interactive risk-stratification and Cost-optimization Online DatabasE (SEPSOT-CODE)


• AH-INF Mid Career Award 2023 (Internal Call):
  The Matrix of Resistance: Unveiling the Mechanisms of Extracellular DNA-Mediated Antimicrobial Protection in Biofilms

RESEARCH NODE 3 SCIENTIFIC GOVERNANCE:

Prof. Stefania Stefani - Research Node 3 Leader
Dipartimento di Scienze Biomediche e Biotecnologiche, Università di Catania (UNICT) - stefania.stefani@unict.it



Stefania Stefani is full professor of Microbiology and Clinical Microbiology and head of the laboratory of Medical Molecular Microbiology and Antibiotic Resistance (MMAR) at the BIOMETEC and at the Policlinico University Hospital at the University of Catania, Italy. She is currently President of the Italian Society of Microbiology (SIM).
Her scientific activity is mainly related to several aspect of antibiotic resistance: from molecular mechanisms and epidemiology to genome studies and characterization of mobile elements carrying resistance genes.
Stefania Stefani has held several positions at the Italian Minister of Health: She is member of the OPERA commission in AIFA (until 2023). She is in the Board of the network of Clinical Microbiology Lab organized by AGENAS and AIFA (2023).
She is also involved in the Scientific Board of the European Society of clinical Micro and ID (ESCMID), the Italian Society of Clinical Microbiology (AMCLI) and of the Italian Society of antimicrobial Therapy (SITA) and stewardship (GISA).
She is Editor in Chief of the Journal of Global Antimicrobial Resistance (JGAR) since 2012 and Editor and reviewer for many other microbiology and ID journals.








Prof. Pierluigi Viale - Research Node 3 Co-Leader
Alma Mater Studiorum - Università degli Studi di Bologna (UNIBO) - pierluigi.viale@unibo.it

Latest News and Updates from Research Node 3:

Active Calls and Opportunities from Research Node 3: