PLASMARE

Platforms for a Monitoring and Analysis Research Ecosystem

Budget: € 9,126,700

Start date: 2026-06-01

End date: 2029-05-31

Current challenges in the field of health highlight close interconnections between biological, environmental, and digital factors. The increasing complexity of health and environmental risks—exacerbated by climate change, the circulation of zoonotic pathogens, and the fragility of agri-food supply chains—calls for a shift towards prevention and response models based on predictive tools and integrated digital solutions. The One Health approach, supported by international organizations such as WHO, FAO, WOAH, and the EU, is based on the combined collection and joint analysis of information from the health, veterinary, environmental, and socioeconomic domains. Implementing the One Health approach requires a significant shift in the strategic vision of health research stakeholders, integrating data and information from a multitude of sources and measurement methodologies. Similarly, the instrumental approaches required for data collection within a One Health framework often require substantial investments to foster the development of multidisciplinary and shared enabling technologies. This is further complemented by the development of innovative therapeutic strategies, which is closely linked to the availability of cutting-edge instrumentation and robust databases for the validation of drug targets. In this context, significant disparities in technological and digital capabilities can be observed in some areas of Southern Italy, where infrastructure networks are often valuable but fragmented and difficult to access, making it challenging to collect, integrate, and fully exploit the available data.

The PLASMARE project (PLAtformS of Monitoring and Analysis Research Ecosystem) promotes the creation of a national infrastructure for the enhancement, dissemination, and adoption of advanced digital solutions to support public health, based on interoperable, accessible, and replicable technological environments. The objective is to establish a distributed ecosystem of tools and services that facilitate the sharing, harmonization, and protection of health, genomic, environmental, and epidemiological data, fostering the use of intelligent technologies for prevention, decision support, and territorial response.

The PLASMARE project is structured into 4 Work Packages (WPs):

WP1 – Unified Foundation for the Sustainability, Strategy, Organization, Leadership, and Attractiveness of MARE (BUSSOLA) is conceived as a set of strategic actions for coordinating and promoting the MARE Ecosystem, aimed at ensuring the full achievement of the objectives and targets of PLASMARE.
WP2 – Advanced Platforms and Environments for Digital One Health (DIGITAL) aims to develop an advanced infrastructure framework to enhance platforms and testing environments capable of addressing the challenges of modern digital medicine, with a focus on cybersecurity, data management, harmonization, and integration, in compliance with One Health principles.
WP3 – Technological Platforms for Parasitological Monitoring, Control, and Screening (MONITOR) aims to strengthen the adoption of advanced infrastructures for rapid screening and health prevention, with a focus on parasitology and in synergy with DOMARE at high-mobility nodes such as ports and airports. The objective is to enhance the capacity to respond to complex epidemiological scenarios by integrating innovative solutions within a One Health framework.
WP4 – Integrated Technological Platforms for Drug Discovery and Testing (DISCOVER) aims to create a modular and flexible platform for drug discovery and testing. Access to the infrastructure of the DISCOVER value chain will be coordinated within the MARE ecosystem through scientific collaborations, integrated services, or high-value-added technological services, in order to accelerate the development of new therapies.

Implemented with the contribution of the European Union under the National Research, Innovation and Competitiveness Programme for the Green and Digital Transition 2021–2027 (PN RIC 21–27), Call for Proposals DD 307 of 18 March 2025, Action 1.1.3b – Support for the validation and networking of forms of aggregation that foster cross-fertilisation among actors within the research system.